DO-HEALTH is a clinical trial

designed to to support healthy aging in European seniors, and to establish whether vitamin D, omega-3 fatty acids, and a simple home exercise program will prevent disease at older age and thereby prolong healthy life expectancy.

DO-HEALTH enrolled 2157 community-dwelling men and women 70 years and older from 7 European cities (Zürich, Basel, Geneva, Toulouse, Berlin, Innsbruck and Coimbra). They were randomized in a 2x2x2 factorial design trial to a simple home exercise program and/or vitamin D, and/or omega-3 fatty acids, over a 3 year period.

This allows to test the benefit of the interventions in the prevention of 5 primary endpoints: the risk of incident non-vertebral fractures, the risk of functional decline, the risk of blood pressure increase, the risk of cognitive decline, and the rate of any infection.

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The DO-HEALTH biobank

provides a treasure for future research on prevention of chronic diseases among the older adult population.

The blood and urine collected for the biobank (serum, plasma, whole blood (for DNA analyses), urine) is stored for up to 30 years after the end of study (last patient, last visit, i.e. 2047).

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All DO-HEALTH participants were extensively assessed and characterized at baseline and during the 3 year follow-up.

If you are interested in a collaboration please complete the form here.

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Browse through all kind of results and publications related to DO-HEALTH, incl. scientific publications and the summaries of past public events.

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See a list of projects that came out of the DO-HEALTH trial, especially MD dissertations and/or take an active brake and GRUUVE.

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